The 13 Best Heart Supplements For Cardiovascular Well-Being



Folate is an essential B vitamin (B9) that, amongst other essential functions in the body, enables the methylation cycle to run smoothly, as the body requires active folate to help convert homocysteine to methionine. Without sufficient folate, homocysteine levels can build up over time, leading to cardiovascular, neurological, and/or immune health issues.

Getting enough folate daily is absolutely critical to keep homocysteine levels in check. The problem is that folks with the MTHFR gene variant (i.e., approximately 50% of the U.S. population!) have a difficult time converting the folate (from food) or folic acid (from certain supplements) into an active form their body can use to support a healthy methylation cycle. 

This is where bioavailability comes in! The activated, methylated form of folate—5-methyltetrahydrofolate (5-MTHF)—can be taken daily to ensure that your body is getting the most optimized form of folate to comprehensively support your methylation cycle and overall cardiovascular health18.* 

Our recommendation: mindbodygreen methylation support+



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